Scientific Name: Rattus norvegicus
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Euarchontoglires-> Glires-> Rodentia-> Myomorpha-> Muroidea-> Muridae-> Murinae
Summary: This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein. [provided by RefSeq, Nov 2015] [NCBI] [Proteinatlas]
Data set information
| Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
|---|---|---|---|---|---|---|
| Vthunter_1001 | 2019.12 | 10X Genomics | Lung | Normal | 5029 | Link |
| Vthunter_1002 | 2019.12 | 10X Genomics | Lung | Normal | 5924 | Link |
| Vthunter_1009 | 2017.11 | Fluidigm C1 | UrogenitalSinus | Normal | 114 | Link |
| Vthunter_110073 | 2019.12 | MARS-seq | TotalBrain | Normal | 2304 | Link |
Featureplot of receptors
Expression: Ubiquitous expression in placenta (RPKM 41.6), heart (RPKM 23.5) and 24 other tissues
